Methylene Dichloride (MDC), also known as dichloromethane, is a commonly used solvent in pharmaceutical manufacturing. While it is not present in finished medicines, it plays an important role during the steps that help make drugs pure, stable, and effective. Why Methylene Dichloride Is Used in Pharmaceuticals Methylene dichloride has properties that make it suitable for […]
Methanol has been used in pharmaceutical manufacturing for decades, and it continues to play a vital role in how medicines are made today. Even as new technologies and alternative solvents emerge, methanol remains a trusted and widely used material across drug development and production. Why Methanol Is Widely Used in Pharmaceuticals Methanol is valued […]
Acetone is one of the most commonly used solvents in pharmaceutical manufacturing. Outside the pharmaceutical world, it is widely recognised for everyday applications such as nail polish and gel polish removal, paint thinning, varnish, and lacquer removal, degreasing metal surfaces, adhesive and ink removal, and cleaning tools and equipment in industrial and household settings. However, […]
Drying is a critical step in solid dosage manufacturing, especially when Isopropyl Alcohol (IPA) is used as a solvent. IPA is preferred in many pharmaceutical processes due to its strong solvency and fast evaporation. However, these same properties also introduce challenges related to safety, residual solvents, and process consistency. Why IPA Is Used in […]
Methanol is one of the most widely used polar solvents in pharmaceutical and biopharmaceutical manufacturing. In recent years, its role has become even more important as the industry shifts towards advanced modalities such as mRNA vaccines, lipid nanoparticle (LNP) systems, viral vectors, and gene-therapy formulations. These products are extremely sensitive to impurities, meaning the quality […]
Nanoparticle and lipid-based formulations (LNPs) have become essential in modern drug delivery, especially for mRNA vaccines, gene therapy products, and targeted therapeutics. These delivery systems allow sensitive molecules to reach their target safely and efficiently. While lipids and polymers form the structure of these nanoparticles, solvents such as acetone play a key role in their […]
Isopropyl Alcohol (IPA) plays a far more central role in pharmaceutical manufacturing than just cleaning and disinfection; it is deeply integrated into processes that define the quality, appearance, stability, and performance of oral solid dosage (OSD) forms, especially tablet coating and solid dose formation. Because IPA comes into direct contact with excipients, coating polymers, pigments, […]
Continuous pharmaceutical manufacturing is transforming the way medicines are produced. Instead of traditional batch methods, continuous processing allows raw materials to move through each step without interruption. This approach offers improvements in efficiency, consistency, safety, and cost. However, when solvents such as Methylene Dichloride (MDC) — also known as Dichloromethane are used in these systems, […]
In pharmaceutical, biotechnology, and healthcare industries, cleanrooms are the backbone of contamination control. Maintaining sterile and particle-free surfaces is essential to ensure product quality and patient safety. Isopropyl Alcohol (IPA) wipes are one of the most commonly used tools for surface cleaning and disinfection in these critical environments. However, not all wipes are created equal, […]
Methylene Dichloride (MDC), also known as dichloromethane, has long been a trusted solvent in the pharmaceutical industry. Its unmatched solvency power, versatility, and performance in chemical synthesis make it indispensable in various drug manufacturing processes. However, MDC also comes with toxicity concerns that demand careful management and adherence to safety and environmental standards. This article […]
In pharmaceutical research and quality control, the precision and reliability of analytical results are vital. Among the many solvents used in assay testing, methanol has earned a reputation as one of the most dependable choices. Whether used in chromatographic techniques like HPLC and GC or in spectroscopic analyses, methanol offers the balance of purity, compatibility, […]
Acetone is one of the most versatile solvents in the pharmaceutical industry used across research, production, formulation, and analytical testing. However, not all acetone is the same. The grade of acetone you choose can make a significant difference in safety, performance, and compliance especially when distinguishing between critical and non-critical pharmaceutical applications. In this article, […]
In pharmaceutical and biotechnology industries, the extraction of bioactive compounds is a crucial step in developing high-value products such as active pharmaceutical ingredients (APIs), alkaloids, vitamins, and natural therapeutics. Achieving high purity and yield from complex biological materials requires solvents that can deliver selective, efficient, and controlled extraction. Methylene Dichloride (MDC), also known as Dichloromethane, […]
In the pharmaceutical industry, oral solid dosage forms (OSDs) such as tablets and capsules remain one of the most preferred and widely used drug delivery systems. The quality, stability, and patient acceptability of these products depend not only on their active ingredients but also on the coating process that protects and enhances them. Among the […]
Freeze-drying, also known as lyophilisation, is one of the most valuable techniques in modern pharmaceutical development. It enables the preservation of heat-sensitive drugs, biologics, and vaccines without compromising their structural integrity or efficacy. While the process seems straightforward on the surface, the choice of reagents and solvents used in lyophilisation plays a significant role in […]